产品展厅
产品展厅
|
应用 |
建议稀释比 |
免疫印迹 (WB) |
1:500-1:2,000 |
免疫组化（石蜡） (IHC (P)) |
1:50-1:200 |
免疫细胞化学 (ICC/IF) |
1:50-1:200 |
|
产品规格
|
|
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthetic peptide of human Acetyl-Histone H3-K9/K14/K18/K23/K27 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2901416 |
Positive Samples: HeLa, NIH/3T3, C6
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
